If they have time, astronauts and cosmonauts will look to plug the leak or close the hatch to the leaking section of the station. (That is how they dealt with a minor leak in the station’s PrK module for a number of years, and it basically worked.) Remember, though, that this is the worst-case scenario, and our crew will run into a hard deadline. Once pressure falls to around 490 mm Hg, NASA says, critical systems risk breaking down. Astronauts could suffer hypoxia, oxygen deprivation so debilitating they could become delirious. It will be a heart-wrenching call, but if nothing else can be done, the crew will need to go to their crew vehicles and leave the ISS.
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"NASA must standardize its approach, increase flight rate safely, and execute on the President’s national space policy. With credible competition from our greatest geopolitical adversary increasing by the day, we need to move faster, eliminate delays, and achieve our objectives," said Isaacman. "Standardizing vehicle configuration, increasing flight rate and progressing through objectives in a logical, phased approach, is how we achieved the near-impossible in 1969 and it is how we will do it again."
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